G6PD5 — Cucumis melo

Summary

MELO3C008985.2, designated CmG6PD5 on melon chromosome 9, encodes a glucose-6-phosphate dehydrogenase (G6PDH) with NADP binding activity. This enzyme is associated with glucose metabolism, the oxidative branch of the pentose pathway, and glutathione metabolism. The protein localises to the cytosol, chloroplast stroma, and the cytoplasmic side of the endoplasmic reticulum membrane. In melon, CmG6PD5 has been linked to chilling stress response, respiration rate, root-knot nematode resistance and susceptibility, salt tolerance, root growth, oxidative stress tolerance, NADPH production, ABA sensitivity, seed oil content, and seed germination. Studies of the Arabidopsis relative G6PD6 connect the family to salt stress tolerance, biomass accumulation, and carbon metabolism, while broader sequence similarity links extend associations to traits including sugar and starch content, water use efficiency, and germination rate.