NSF — Cucumis melo

Summary

MELO3C009349.2 (CmNSF) on melon chromosome 5 encodes an AAA-ATPase of the CDC48 family, with annotated AMP deaminase, [pyruvate kinase]-phosphatase, proteasomal ATPase, and ubiquitin ligase substrate adaptor activities, and SNARE and polyubiquitin-modification-dependent protein binding. The gene is associated with protein complex disassembly, mitotic spindle breakdown, protein dislocation from the ER, membrane fusion, Golgi organization, protein secretion, and responses to freezing and misfolded proteins. It is linked to organ and meristem growth, pollen maturation, microsporogenesis, female gamete generation, and regulation of meristem organization. Traits connected to CmNSF include plant male sterility, seed longevity, leaf shattering, viral disease response, herbicide and zinc sensitivity, nitrate uptake, stem elongation, flowering time, and disease tolerance. The protein localizes to the p97-Ufd1-Npl4 complex, nuclear envelope, cell plate, spindle, and mitochondrial outer membrane.