M2 — Cucumis melo

Summary

MELO3C009493.2, designated CmM2 on melon chromosome 5, encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) with a cyclophilin-like domain. The product is associated with diverse molecular functions including cyclosporin A binding, salicylic acid binding, histone and chromatin binding, peroxidase activity, and U2/U5 snRNA binding. It has been linked to protein proline isomerization, regulation of ARF protein signal transduction, alternative mRNA splicing, basipetal auxin transport, and responses to light intensity, chlorate, and sulfate starvation. Associations with agronomic traits include variegated leaf, starch grain synthesis, sucrose content, photosynthetic rate, respiration rate, heat stress tolerance, and disease resistance. Studies of related genes in other species link the family to drought response, cold stress tolerance, hydrotropism, and embryo patterning.