CAD2 — Cucumis melo

Summary

MELO3C005674.2 (CmCAD2) on melon chromosome 10 encodes a glutamate-cysteine ligase and contains a glutamine synthetase/guanido kinase catalytic domain. The gene is associated with glutathione anabolism, defense responses to bacteria, fungi, insects, and ozone, as well as responses to cadmium, heat, and jasmonic acid. It is linked to lignin anabolism, glucosinolate anabolism, flower development, root development, and localizes to the chloroplast stroma, plastid, and cytosol. Associations also include drought tolerance, photosynthetic rate, ethylene sensitivity, pathogen resistance, auxin transport, cadmium tolerance, downy mildew resistance, chilling tolerance, and stomatal closure. Studies of related genes in other species link the family to glutathione content, cadmium sensitivity, nematode resistance, and flowering time.