WRKY12 — Cucumis melo

Summary

MELO3C005937.2, also known as CmWRKY12 or WRKY12, encodes a WRKY transcription factor on melon chromosome 7. The protein localises to the nucleus, binds sequence-specific DNA and RNA Polymerase II cis-regulatory regions, and can homodimerise. In melon, CmWRKY12 is associated with fruit bitterness, upregulation of sclerenchyma cell differentiation, regulation of lignin anabolism, plant-type cell wall biogenesis, positive regulation of leaf senescence and autophagy, cellular thermotolerance, stress response to cadmium ion and chitin, systemic acquired resistance, and abscisic acid and gibberellic acid signalling. It is also linked to submergence response and tolerance, shoot axis branching, root oxidative activity, seedling growth, disease tolerance, salt tolerance, cadmium accumulation and tolerance, stem development and stiffness, secondary cell wall formation, iron accumulation in seeds, flowering time, and resistance to fungal pathogens including Botrytis cinerea.