M2 — Cucumis melo

Summary

MELO3C006176.2, designated CmM2 on melon chromosome 7, encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) with cyclosporin A binding, peroxidase activity, and additional annotated molecular functions including GTP:GDP antiporter activity, U5 and U2 snRNA binding, and histone and chromatin binding. The gene is associated with diverse biological processes such as protein proline isomerization, regulation of ARF protein signal transduction, alternative mRNA splicing, response to light intensity, basipetal auxin transport, and cellular response to sulfate starvation. It is linked to agronomically relevant traits including variegated leaf, starch grain synthesis, respiration rate, photosynthetic rate, sucrose content, temperature stress response, herbicide sensitivity, root hair length, and jasmonic acid content. Localization evidence connects the product to the Golgi stack, spliceosome, thylakoid lumen, and proteasome. Studies of related genes in other species link the family to hydrotropism, phototropism, cold stress tolerance, embryo patterning, and drought response.