MLO — Cucumis melo

Summary

MELO3C005038.2, designated CmMLO (also known as MLO3), encodes a calmodulin-binding protein localised to the membrane and nucleus in melon (Cucumis melo) chromosome 13. The gene is associated with defense response and mating biological processes. In melon, CmMLO has been connected to leaf senescence and downy mildew resistance. Studies of related MLO family members in other species link this gene family to powdery mildew susceptibility and target leaf spot resistance in cucumber, as well as callose deposition and systemic acquired resistance in Arabidopsis. The family is also associated with responses to rice narrow brown leaf spot, cucurbit downy mildew, and wheat powdery mildew, along with leaf senescence traits.