CAD1 — Cucumis melo

Summary

MELO3C005258.2, designated CmCAD1, encodes a MACPF domain-containing protein of the CAD1/NSL1-like family on melon chromosome 10. The gene is associated with defense response by callose deposition, regulation of salicylic acid metabolic process, immune response, programmed cell death, and response to fungi. It is also linked to water transport, lignin anabolism, dedifferentiation, response to sorbitol, flower and root development, and salinity response. The product localises to the extracellular region, plasmalemma, and nucleus. CmCAD1 is associated with lignin content, drought tolerance, and multiple phenotypes including dwarfism with necrotic leaf lesions, cell death regulation, heavy metal tolerance (cadmium, zinc, arsenic), decreased salt stress tolerance, disease resistance, immunity to Pseudomonas syringae, salicylic acid accumulation, and phyllosphere microbiota composition.