M2 — Cucumis melo

Summary

MELO3C005188.2, also known as CmM2, encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) on melon chromosome 10. The product possesses cis-trans proline isomerase activity, cyclosporin A binding, and is annotated with salicylic acid binding, peroxidase activity, and GTP:GDP antiporter activity. CmM2 is associated with diverse biological processes including protein proline isomerization, regulation of ARF protein signal transduction, oxidative phosphorylation, alternative mRNA splicing, and responses to light intensity and sulfate starvation. It localizes to the Golgi stack, thylakoid, and proteasome. The gene is linked to numerous agronomic traits such as variegated leaf, starch grain synthesis, respiration rate, photosynthetic rate, sucrose content, temperature stress response, herbicide sensitivity, root hair length, and jasmonic acid content. Studies of related genes in other species connect the family to drought response, cold stress tolerance, hydrotropism, phototropism, embryo patterning, and resistance to Botrytis cinerea.