KCS2 — Camelina sativa

Summary

CsKCS2 (CSA16G003160) on Camelina sativa chromosome 16 encodes a protein with domains including FAE1-type polyketide synthase, 3-ketoacyl-CoA synthase, ACP synthase III C, and thiolase-like. It is annotated with acetoacetyl-CoA reductase, trans-2-enoyl-CoA reductase (NADPH), ketoreductase, 3-hydroxyacyl-CoA dehydratase, naringenin-chalcone synthase, and acyltransferase activities. The protein localizes to the endoplasmic reticulum membrane and fatty acid elongase complex. CsKCS2 is associated with very-long-chain fatty acid and wax biosynthesis, cutin-based cuticle development, suberin biosynthesis, polyketide and flavonoid anabolism, sphingolipid metabolism, trichome papilla formation and branching, polar cell growth, osmotic and wounding responses, and regulation of cell division. It has been linked to drought and salt tolerance, male sterility, root morphology and thickness, leaf composition, embryo development, and high temperature stress response. Studies of related genes in other species connect the family to cuticular wax formation, root suberin biosynthesis, and pollen fertility.