CYP — Camelina sativa

Summary

CSA16G003540, designated CYP, encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) with EC 5.2.1.8 activity and cyclosporin A binding capability. This enzyme is associated with protein folding and regulation of protein refolding, and has been linked to detoxification. The gene product is associated with responses to abscisic acid, salt, and mannitol, as well as activation of salinity response. It localizes to multiple cellular compartments including the chloroplast stroma, cytosol, plasmalemma, cytoplasm, and nucleus. Studies of related genes in other species link the cyclophilin family to stress tolerance mechanisms, though these associations are not yet established in Camelina sativa.