KCR1 — Camelina sativa

Summary

CsKCR1 (CSA16G027660) on Camelina sativa chromosome 16 encodes a protein with acetoacetyl-CoA reductase, trans-2-enoyl-CoA reductase (NADPH), and multiple 17-beta-hydroxysteroid dehydrogenase activities, belonging to the short-chain dehydrogenase/reductase (SDR) family and the VLCFA-steroid dehydrogenase domain. It is associated with very-long-chain fatty acid and wax biosynthesis, suberin biosynthetic process, cuticle development, steroid and sphingolipid metabolism, and trichome branching and papilla formation. The protein localizes to the endoplasmic reticulum membrane and the fatty acid elongase complex. CsKCR1 is linked to traits including drought and salt tolerance, male sterility, root morphology and thickness, leaf composition, embryo development, and high temperature stress response. Studies of related genes in other species connect the family to very-long-chain fatty acid elongation, cuticular wax deposition, pollen fertility, embryo viability, and root hair elongation.