NIM1 — Brassica oleracea var. botrytis

Summary

BoNIM1 (BOLND125_C09P017870.1) on cauliflower chromosome 9 encodes a transcriptional co-regulator with oxidoreductase activity acting on a sulfur group of donors with disulfide as acceptor, salicylic acid binding, calmodulin binding, and protein kinase activity. It contains BTB/POZ, ankyrin repeat, and NPR1/NIM1-like domains. The gene is associated with regulation of systemic acquired resistance, salicylic acid-mediated signaling, defense responses to bacteria and insects, and response to herbivores. It has been linked to numerous disease resistance traits including bacterial blight, stripe rust, powdery mildew, and Cercospora leaf spot responses, as well as drought sensitivity, photosynthetic rate, iron content, and inflorescence morphology. Studies of related genes in other species link the family to pathogen resistance, systemic acquired resistance, and salicylic acid-responsive gene expression.