CML37 — Brassica oleracea var. botrytis

Summary

BoCML37, a gene on cauliflower chromosome 9, encodes a calmodulin-like protein with EF-hand domains and calcium ion binding activity. It is also annotated with ABC-type transporter activities, including auxin efflux and cadmium ion transmembrane transport. The gene is associated with diverse biological processes such as regulation of defense response by callose deposition, response to oomycetes, PTI signaling, cellular detoxification, cadmium transport, sodium ion homeostasis, and regulation of lateral root development and auxin-mediated signaling. It has been linked to traits including auxin content and sensitivity, disease tolerance, salt tolerance, root morphology, drought stress tolerance, herbivore defense, and jasmonate accumulation. The protein is localized to multiple cellular compartments including the plasma membrane, cytoplasm, nucleus, endoplasmic reticulum, chloroplast envelope, and mitochondria. Studies of related genes in other species link the family to drought stress response, pathogen resistance, and heavy metal resistance.