PI3K — Brassica oleracea var. botrytis

Summary

BoPI3K, the cauliflower gene on chromosome 9, encodes a phosphatidylinositol 3-kinase of the VPS34 class III type, containing PI3K catalytic and accessory domains, a C2 domain, and a serine/threonine kinase domain. The encoded protein is associated with phosphatidylinositol 3-phosphate biosynthesis, macroautophagy, pexophagy, anti-apoptosis, TOR signaling, endocytosis, and phosphoinositide-mediated signaling. It is linked to responses to salt stress, reactive oxygen species metabolism, regulation of stomatal closure, activation of defence response to bacteria, and microgametogenesis. The protein localises to endosome and Golgi membranes, the PAS, and TOR and PI3K complexes. Observed associations include leaf senescence, pollen germination and development, root hair growth, proline accumulation, and heat stress recovery. Studies of related genes in other species link the family to plant growth, disease resistance, stomatal closure, and male gametophyte transmission.