PEUP2 — Brassica oleracea var. botrytis

Summary

BoPEUP2 (PEUP2, ATG18A) on cauliflower chromosome 4 encodes a PROPPIN family protein containing WD40 repeats. The product is annotated with protein binding activity and localises to the cytosol and nucleus. It is associated with regulation of autophagy, including positive regulation, as well as nuclear export, response to starvation, leaf senescence, osmotic and salinity responses, oxidative stress, and defence response to fungi. Phenotype associations include autophagy, powdery mildew resistance, cell death, protein degradation, resistance to necrotrophic fungal pathogens and Botrytis cinerea, disease resistance, peroxisome degradation, and restored IBA responsiveness. Related genes in other species link the family to nutrient stress tolerance, salt tolerance, oxidative stress tolerance, pexophagy, hydrotropic response, senescence, and fungal pathogen resistance.