RDR6 — Brassica oleracea var. botrytis

Summary

BoRDR6 (BOLND125_C04P036230.1_BOLND125_V1) on cauliflower chromosome 4 encodes an RNA-dependent RNA polymerase (RdRP) with RNA-binding domains, conferring RdRP activity and ubiquitin ligase binding. This gene is associated with posttranscriptional gene silencing by RNA, including trans-acting siRNA processing, siRNA processing, and virus-induced PTGS. It is linked to vitamin A, vitamin E, chlorophyll, and wax anabolism, as well as vegetative phase change, maintenance of shoot apical meristem identity, carpel and pistil development, pollen recognition, heat acclimation and response to heat, and antiviral response. Associations include leaf morphology, chlorophyll and anthocyanin content, viral disease response, and abiotic stress response traits. The protein localises to the cytoplasm, nucleus, endoplasmic reticulum, stress granules, and the RNA-dependent RNA polymerase complex. Studies of related genes in other species link the family to antiviral RNA silencing, miRNA activity, disease resistance, self-incompatibility, and leaf polarity.