CAD2 — Brassica oleracea var. botrytis

Summary

BoCAD2 on cauliflower chromosome 1 encodes a glutamate-cysteine ligase. The protein contains a glutamylcysteine ligase plant-type domain and localises to the chloroplast stroma, plastid and cytosol. This gene is associated with glutathione anabolism, defence responses to insects, bacteria and fungi, callose deposition, ozone and heat responses, seed germination, flower development, and indole phytoalexin and glucosinolate anabolism. It is linked to cadmium tolerance, root development, shoot branching, axillary meristem formation, embryo development, anthocyanin accumulation, leaf senescence, stomatal closure, basal thermotolerance, and resistance to downy mildew and Alternaria brassicicola. Studies of related genes in other species link the family to glutathione content, cadmium sensitivity, flowering time, zinc transport, oxidative stress tolerance, and nematode resistance.