ALS — Brassica oleracea var. botrytis

Summary

BoALS (BOLND125_C01P037300.1) on cauliflower chromosome 1 encodes an acetolactate synthase large subunit, a thiamine pyrophosphate-dependent enzyme. The gene product exhibits acetolactate synthase, pyruvate decarboxylase and 2-hydroxyacyl-CoA lyase activities, binds TPP, FAD and magnesium, and localises to the chloroplast stroma as part of the acetolactate synthase complex. BoALS is associated with branched-chain amino acid, valine and fatty acid alpha-oxidation metabolism, response to herbicide, hypersensitivity, protein transport, signal transduction and homeostasis. The gene is linked to photosynthetic rate and herbicide tolerance. Studies of related genes in other species connect the family to imidazolinone and sulfonylurea herbicide sensitivity and resistance, as well as to seed weight, plant height, starch and protein content, and heterosis.