TRFL9 — Brassica oleracea var. botrytis
Summary
BoTRFL9 (TRFL9) on cauliflower chromosome 1 encodes a protein with a Myb domain, SANT/Myb domain, and ubiquitin-like domains, and is annotated with anthranilate phosphoribosyltransferase activity, DNA bending, telomeric repeat binding, and RNA binding. It is associated with regulation of telomere maintenance, positive regulation of telomere maintenance via telomerase, cellular response to UV-C, tryptophan formation, stem cell population maintenance, root meristem growth, and meristem maintenance. The gene is linked to seed viability, flowering time, disease tolerance, and phenotypes including tryptophan auxotrophy, stunted growth, reduced fertility, and telomere shortening. It localizes to the nucleus, chromosome telomeric region, and plastid. Related genes in other species are linked to telomere length regulation, cell death, and plant viability.
Annotations
- Chromosome
- 1
- Related genes
- TRFL9, TBP1, ATPOT1, TRP1, ETL1, AT4G33945, TERT
- GO terms
- DNA Binding, Bending, Telomerase Activity, DNA Damage Response, Anthranilate Phosphoribosyltransferase Activity, Plastid, Nucleus, Protein Homodimerization Activity, GO:0009507
- Publications
- 20226671, 26779251, 35560426, 19214203, 19783822, PMID:18431481, 12853623, 22623495
- Traits
- tryptophan biosynthesis, Progressive Telomere shortening with Progressive Telomere Shortening, Telomere Shortening Similar to Related Mutants, Telomere Shortening with Failure to Elongate Telomeres, Telomeres Maintain Length and Banding Profile in Double Mutant, Accelerated Telomere Loss, Early Growth Degeneration, Chromosomal Bridges, Decreased Root Meristem Size Correlating with Telomere Length Reduction, Anaphase Bridges and Chromosomal Defects in Late Generation Mutants