CYP81F1 — Brassica oleracea

Summary

BoCYP81F1 (CYP81F1) on cabbage chromosome 6 encodes a cytochrome P450 monooxygenase with isoflavone 2'-hydroxylase, piperitol synthase, and oxidoreductase activities, binding heme and iron. The gene is associated with indole glucosinolate metabolism and glucosinolate anabolism, as well as seed germination. Its product localises to the endoplasmic reticulum membrane and also has connections to mitochondria. BoCYP81F1 is linked to camalexin accumulation. Studies of related genes in other species connect the CYP81F1 family to cytoplasmic male sterility and heterosis, though these associations are not yet established in cabbage.

Annotations

Chromosome
6
Related genes
CYP81F1, CYP81E8
GO terms
glucosinolate anabolism, Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, iron binding, Isoflavone 2'-hydroxylase Activity, Heme Binding, Membrane, ER membrane, mitochondria
Publications
20736450, 15295017, PMID:16618929, 16307366, 15860015, PMID:21317374, PMID:26802248, PMID:26802249
Traits
other miscellaneous trait, clim-pet1, clim-pet2, clim-pet12, clim-pet11, camalexin accumulation, cytoplasmic male sterility, heterosis