CYP81F1 — Brassica oleracea

Summary

BoCYP81F1 (CYP81F1) on cabbage chromosome 6 encodes a cytochrome P450 monooxygenase with isoflavone 2'-hydroxylase, piperitol synthase, and 4'-methoxyisoflavone 2'-hydroxylase activities, and is associated with heme and iron binding. The gene is associated with indole glucosinolate metabolism and glucosinolate anabolism, as well as seed germination. Its product localises to the endoplasmic reticulum membrane and also has associations with mitochondria. BoCYP81F1 is associated with camalexin accumulation. Studies of related genes in other species link the family to cytoplasmic male sterility and heterosis, though these associations are not established for cabbage itself.