ASY1 — Brassica oleracea

Summary

BoASY1 (BOLC102_C06P042780.1) on cabbage chromosome 6 encodes a HORMA-domain-containing protein. The gene product is associated with protein binding and localises to the nucleus, chromosomes, chromatin, centromere complex and nucleolus. BoASY1 is associated with meiotic cell cycle progression, including leptotene, zygotene, pachytene, diplotene, metaphase and interphase, as well as meiotic DNA double-strand break formation, homologous recombination, chiasma assembly, homologous chromosome pairing, microtubule assembly and the pachytene checkpoint. The gene has been linked to meiotic recombination, chiasma formation, crossover frequency, crossover interference and assurance, chromosomal and genomic stability, and chromosome axis assembly. It is also associated with arsenic concentration. Related genes in other species are linked to meiotic crossover formation and chromosome axis formation.