CYP81F4 — Brassica oleracea

Summary

BoCYP81F4 (BOLC102_C03P085090.1) on cabbage chromosome 3 encodes a cytochrome P450 monooxygenase with isoflavone 2'-hydroxylase, piperitol synthase, and related oxidoreductase activities. The gene is associated with indole glucosinolate metabolism and glucosinolate anabolism, and its product localises to the endoplasmic reticulum membrane. Studies of related genes in other species link the CYP81F family to additional cytochrome P450 activities such as EC 1.14.14.88–90 and EC 1.14.19.74, though these specific functions are not yet established in cabbage. The gene is also connected to CYP81E1, a related P450 family member.

Annotations

Chromosome
3
Related genes
CYP81F4, CYP81E1, CYP81E8
GO terms
glucosinolate anabolism, Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, iron binding, Isoflavone 2'-hydroxylase Activity, Heme Binding, Membrane, ER membrane, ER
Publications
15695462, PMID:15634198, 15295017, PMID:16618929, PMID:21317374, PMID:9790908, PMID:27783045, PMID:29614820