HA2 — Brassica oleracea

Summary

BoHA2 (HA2, AHA2) on cabbage chromosome 3 encodes a P-type ATPase (subfamily IIIA) with proton-transporting ATPase activity, also annotated for guanylyl cyclase, transmembrane signaling receptor, peptide receptor, and calmodulin-binding functions. It is associated with proton export across the plasma membrane, cell pH regulation, response to pH reduction, very-long-chain fatty acid metabolism, negative regulation of leaf senescence and programmed cell death, phloem transport, leaf vascular tissue pattern formation, and defense responses. The gene is linked to traits including alkali soil sensitivity, photosynthetic rate, water stress and temperature stress responses, bacterial disease response, leaf vein morphology, root and shoot development, iron and arsenic content, brassinosteroid and auxin sensitivity, and seed growth. Studies of related genes in other species connect the family to plasma membrane H⁺-ATPase activity, cell elongation, root growth, salt and drought tolerance, and plant immunity.