IRT1 — Brassica napus

Summary

BnIRT1 (DARMORV10_C07P50540.1) on chromosome C07 of oilseed rape encodes a ZIP family metal transporter with iron channel activity and transmembrane transporter activities for copper, manganese, zinc, and cadmium ions. The gene is associated with metal homeostasis, including iron deficiency tolerance and response, as well as accumulation and transport of iron, cadmium, zinc, and nickel. It has been linked to photosynthetic rate, chlorophyll and carotenoid content, leaf chlorosis, stomatal resistance, germination rate, and plant growth and development traits. Additional associations include pollen germination, cellular response to hypoxia, response to bacteria, signal transduction, and downregulation of abscisic acid-mediated signaling. The encoded protein localizes to the plasmalemma, endosome, late endosome membrane, TGN, and nucleus, and is linked to ESCRT I complex and MVB formation. Related genes in other species are associated with iron uptake, transport, and translocation, as well as cadmium sensitivity and nickel accumulation.