HSP83 — Brachypodium distachyon

Summary

BdHSP83 (BRADI_5G02037V3) encodes a heat shock protein 90 (HSP90) family member on chromosome 5 of Brachypodium distachyon. The product contains HSP90 and HATPase domains and has been annotated with ATP-dependent protein folding chaperone, transcription regulator, DNA polymerase, protein kinase, and cis-trans proline isomerase activities, as well as phosphatidylinositol phosphate binding. It is associated with cellular thermotolerance, UV protection, response to unfolded protein, brassinosteroid signalling, root hair differentiation, autophagy, and DNA repair pathways including base-excision and nucleotide excision repair. The protein localises to the perinuclear cytoplasm, chloroplast outer membrane, ER lumen, and SCF ubiquitin ligase complexes. Associations with maturity time, flowering, stress responses, hormone sensitivities, starch grain synthesis, and inflorescence morphology have been noted. Studies in related genes in other species link the HSP90 family to thermotolerance, pathogen resistance, drought memory, and male fertility.