HSP70 — Beta vulgaris subsp. vulgaris

Summary

BVRB_1G010020 (HSP70) on sugar beet chromosome 1 encodes a heat shock protein 70 family member with ATP hydrolase activity, ATP binding, heat shock protein binding, and protein folding chaperone functions. The gene is associated with protein refolding, the ERAD pathway, the unfolded protein response, and protein folding in the ER. It is linked to cytoskeleton and actin cytoskeleton organization, glycan and carbohydrate metabolism, detoxification, and responses to stress, heat, and virus, as well as immune response. Localization evidence links the product to the ER lumen and chaperone complex, chloroplast membrane, tonoplast, cytoplasm, and nucleus. The gene is also associated with zinc concentration. Studies of related genes in other species link the family to similar ER stress and chaperone functions.