HSP70 — Beta vulgaris subsp. vulgaris

Summary

BVRB_1G010000 (HSP70) on sugar beet chromosome 1 encodes a member of the heat shock protein 70 family, a chaperone with ATP hydrolase activity that binds ATP and heat shock proteins, and is annotated as a protein folding chaperone. The gene is associated with protein refolding, the ERAD pathway, the unfolded protein response (erUPR), detoxification, and responses to heat, stress, virus, and the immune response. It is also linked to cytoskeleton and actin cytoskeleton organization, glycan biosynthesis, and carbohydrate metabolism. Localization evidence connects the encoded protein to the ER lumen and chaperone complex, chloroplast membrane, cytoplasm, nucleus, and membrane. The gene has been associated with zinc concentration. Related genes in other species, including BiP3 and HSC-2, link the family to similar chaperone functions.