MYCGR3G35076 — Zymoseptoria tritici

Summary

MGYAP1 (yap1) on Zymoseptoria tritici chromosome 1 encodes a bZIP transcription factor that binds DNA and acts as an RNA polymerase II-specific transcriptional activator. The gene is associated with the regulation of diverse biological processes, including asexual and sexual sporulation, immune evasion, and responses to singlet oxygen, cadmium, and amino acid starvation. It is linked to the anabolism of secondary metabolites such as sterigmatocystin, emericellin, and shamixanthone, as well as to the inhibition of asperthecin formation. The encoded protein localises to the nucleus, cytoplasm, chromatin, and transcription regulator complexes. MGYAP1 is also associated with oxidative stress. Studies of related genes in other species link the YAP1 family to virulence, though pathogenicity effects in Z. tritici remain uncharacterised.