GPX1 — Zea mays

Summary

ZM00001EB429430 (GPX1, ZmGPX1) on maize chromosome 10 encodes a protein with phospholipid-hydroperoxide glutathione peroxidase activity (EC 1.11.1.12), glutathione peroxidase activity, and other annotated molecular functions including D-lactate dehydratase activity, calcium-dependent protein serine/threonine phosphatase activity, and protein kinase activator activity. It contains a thioredoxin domain and glutathione peroxidase active-site motifs. The gene is associated with glutathione redox reactions, cofactor biosynthesis, and metabolism. It is linked to numerous agronomic traits including root yield, spike weight, seedling vigor, grain filling period, seed yield, drought sensitivity, seed viability, carotenoid content, leaf water potential, and cell membrane stability. Associations also include oxidative stress tolerance, photosynthesis, leaf morphology, bacterial resistance, ABA sensitivity, salt stress tolerance, flowering time, and ion homeostasis. The encoded protein localizes to the chloroplast thylakoid membrane, endomembrane system, stress granules, and the preprophase band. Studies of related glutathione peroxidase family members in Arabidopsis and rice link the family to oxidative stress response, heat and cold stress tolerance, drought tolerance, abscisic acid signaling, salt tolerance, and pathogen susceptibility.