GB1 — Zea mays

Summary

ZM00001EB052290, also known as GB1 or ZmIRK, encodes a protein containing WD40 repeat domains and is annotated with diverse molecular functions including transmembrane transporter activities for N-methylnicotinate, nicotinate, fructose, and glucose, as well as ubiquitin-like protein ligase activity and RNA endonuclease activity. The gene is associated with the heterotrimeric G-protein complex and vacuolar membrane localisation. It has been linked to numerous biological processes such as autophagy in response to ER stress, root meristem specification, seed oilbody biogenesis, and regulation of seed size. Associations with agronomically relevant traits include ear diameter, seed protein content, leaf dry weight, shoot elongation under submergence, nitrogen content, oleic acid content, root branching, and drought tolerance. Studies of related genes in other species link the family to the unfolded protein response, ER stress tolerance, and pathogen defence.