ERD8 — Triticum turgidum subsp. durum

Summary

TRITD5AV1G149830 (ERD8) on durum wheat chromosome 5A encodes a heat shock protein 90 (Hsp90) family member with ATP-dependent protein folding chaperone activity, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase activity, and transcription regulator activity. The gene is associated with powdery mildew resistance in durum wheat and linked to diverse processes including cellular response to brassinosteroid stimulus, auxin metabolism, UV protection, chloroplast localization, cytosol-to-ER transport, and gene silencing by miRNA. Associations extend to maturity time, reproductive growth, starch grain synthesis, seed viability, and responses to various pathogens including downy mildew, Fusarium, and Botrytis cinerea. The protein localizes to the chloroplast outer membrane, ER lumen, proteasome, and perinuclear cytoplasm.