ICDH — Triticum turgidum subsp. durum

Summary

TRITD3AV1G157620 (ICDH, TtICDH) on durum wheat chromosome 3A encodes an isocitrate dehydrogenase with NADP and NAD isocitric dehydrogenase activity (EC 1.1.1.42), belonging to the isocitrate dehydrogenase NADP domain family. The gene is associated with NADPH regeneration, NADP and NAD metabolism, isocitrate metabolism, the glyoxylate cycle, and the TCA cycle. It has been linked to brassinosteroid-mediated signalling, defence response to bacteria, and response to zinc. The encoded protein localises to chloroplast thylakoid and stroma, mitochondria, plastid, cytosol, apoplast, and plasmodesma. Associations include proline content, salinity tolerance, photosynthetic rate, root morphology, histone methylation, redox homeostasis, and leaf hydraulic conductivity. Studies of related genes in other species connect the family to drought tolerance, chlorophyll content, net photosynthetic rate, and disease tolerance.