ADH — Triticum turgidum subsp. durum

Summary

TRITD2AV1G051740 (TtADH) on durum wheat chromosome 2A encodes an alcohol dehydrogenase-like protein with S-(hydroxymethyl)glutathione dehydrogenase and S-nitrosoglutathione reductase activities. The gene is associated with responses to hypoxia, flooding, hydrogen peroxide, and heat acclimation, as well as seed development, programmed cell death, and cellular respiration. It has been linked to drought tolerance, salinity response, low temperature stress, leaf senescence, disease tolerance, and herbicide sensitivity. Associations also include photosynthetic rate, nitrogen content, and submergence tolerance. The encoded protein localizes to the cytosol, plastid, mitochondria, nucleus, and plasmalemma. Studies of related genes in other species link the family to hypoxia tolerance, formaldehyde detoxification, and nitric oxide signaling.