GPX1 — Triticum aestivum

Summary

TRAESCS2D02G407700 (TaGPX1) on wheat chromosome 2D encodes a phospholipid-hydroperoxide glutathione peroxidase (PHGPX6) with glutathione peroxidase activity (EC 1.11.1.12), containing a thioredoxin domain and thioredoxin-like superfamily. The gene is associated with cellular oxidant detoxification, the ascorbate-glutathione cycle, and responses to oxidative stress, osmotic stress, and external biotic stimuli. It has been linked to traits including freezing stress response, flour color, relative chlorophyll content, vegetative vigor, grain protein content, seed yield, grain filling period, and wheat powdery mildew disease response. Additional associations include photosynthesis, oxidative stress tolerance, bacterial resistance, and chloroplast redox homeostasis. The gene is also connected to nitrogen utilization, proline metabolism, and flavonoid metabolism. Studies of related genes in other species link the GPX family to drought, salt, and cold stress tolerance, as well as abscisic acid signaling and root development.