VTL1 — Triticum aestivum

Summary

TRAESCS2D02G588000, designated TaVTL1 on bread wheat chromosome 2D, encodes a member of the Ccc1 family with iron ion sequestering activity, manganese ion transmembrane transporter activity, and iron channel activity. The protein localises to the vacuolar and ER membranes. TaVTL1 is associated with cellular iron and manganese ion homeostasis, response to iron, transition metal transport, and response to karrikin and nitrate. It has been linked to vacuole organisation, positive regulation of flavonoid anabolism, and regulation of the hypersensitive response. Agronomically, the gene is associated with iron concentration in roots and shoots, and with iron accumulation. Studies of related genes in other species connect the family to iron homeostasis and seed iron concentration.