CYP — Sorghum bicolor

Summary

SORBI_3010G257800, designated SbSQN and also known as CYP, encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) on sorghum chromosome 10. The protein contains a cyclophilin-type PPIase domain and is annotated with diverse molecular functions including GTP:GDP antiporter activity, U5 and U2 snRNA binding, cyclosporin A binding, histone binding, chromatin binding, and calcium ion binding. SbSQN is associated with the regulation of ARF protein signal transduction, protein phosphorylation and refolding, basipetal auxin transport, establishment of planar polarity, embryonic pattern specification, and alternative mRNA splicing via the spliceosome. It is associated with variegated leaf, bacterial disease response, temperature stress response, starch grain synthesis, sucrose content, phototropism, root hair length, chloroplast development, jasmonic acid content, arsenic concentration, cold tolerance, oxidative stress response, leaf senescence, and seed growth and development. The gene is also linked to root development, auxin transport, gravitropism, lateral root initiation, and embryo apical-basal patterning.