CYTME2 — Sorghum bicolor

Summary

SORBI_3009G069600 (CYTME2) on sorghum chromosome 9 encodes a protein with malate dehydrogenase (decarboxylating) (NAD+) activity, malate dehydrogenase (decarboxylating) (NADP+) activity (EC 1.1.1.40), and oxaloacetate decarboxylase activity, and is associated with metal ion binding, NAD binding, microtubule binding, and protein binding. The gene is associated with C4 photosynthesis, malate transport and metabolism, the oxidative pentose pathway, auxin and brassinosteroid signaling, and responses to cadmium, osmotic stress, and detoxification. It localizes to multiple compartments including the cytosol, plastid, mitochondria, and cell wall. CYTME2 is linked to photosynthetic rate, water use efficiency, drought tolerance, stomatal resistance, and respiration rate. Phenotypic associations include aluminum tolerance, salt and osmotic stress responses, root development, seed germination, flowering time, and pathogen resistance. Studies of related genes in other species link the family to growth, primary metabolism, and salt stress tolerance.