MSD1 — Sorghum bicolor

Summary

SORBI_3009G093200 (MSD1) on sorghum chromosome 9 encodes a manganese/iron superoxide dismutase (EC 1.15.1.1) with superoxide dismutase activity, binding manganese, copper, and other metals. The enzyme localizes to mitochondria, the apoplast, vacuole, and cytosol. MSD1 is associated with reactive oxygen species anabolism, removal of superoxide radicals, and responses to oxidative stress, abscisic acid, herbicides, xenobiotic stimuli, zinc, and osmotic stress. It is linked to inflorescence and embryo development, grain number and yield, spikelet fertility, jasmonic acid content and biosynthesis, photosynthetic rate, antioxidant defense, arsenic tolerance, and root architecture. Studies of related genes in other species connect the family to root growth, superoxide detoxification, and mitochondrial redox homeostasis.