CHS — Sorghum bicolor

Summary

SORBI_3008G013500 (CHS) on sorghum chromosome 8 encodes a chalcone synthase, a type III polyketide synthase with N-terminal and C-terminal chalcone/stilbene synthase domains and a thiolase-like domain. The enzyme exhibits naringenin-chalcone synthase, biphenyl synthase, phloroisovalerophenone synthase, and bisdemethoxycurcumin synthase activities, along with acyltransferase and homodimerization activities. CHS is associated with chalcone, flavonoid, and polyketide biosynthesis, secondary metabolism, pigmentation, UV protection, response to UV-A, nitrogen fixation, and nitric oxide storage. The protein localizes to the cytoplasm. Studies of related genes in other species link the family to EC numbers 2.3.1.74, 2.3.1.156, and 2.3.1.211.