CYP51 — Sorghum bicolor

Summary

SORBI_3008G025700 (SbCYP51) encodes a cytochrome P450 family protein with sterol 14-demethylase, protopanaxadiol 6-hydroxylase, and ent-kaurenoic acid monooxygenase activities, and is associated with sterol and brassinosteroid metabolism, demethylation, saponin and terpenoid biosynthesis, and response to fungal molecules. The gene is linked to endoplasmic reticulum, Golgi, and membrane localization, as well as embryo development and digestion. Associations include sterol biosynthesis, stomatal development, hypocotyl elongation, membrane integrity, seedling growth and viability, oxidative stress tolerance, leaf senescence, and chloroplast development. Studies of related genes in other species connect the family to plant height, growth, lifespan, and aluminum tolerance, as well as seed development, grain yield, and leaf and pollen traits.

Annotations

Chromosome
8
Related genes
CYP51
GO terms
Digestion, iron binding, Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Sterol 14-demethylase Activity, Response To Molecule Of Fungal Origin, Monooxygenase Activity, ER, Golgi complex
Publications
23335967, 10855798, 37340595, PMID:17317660, PMID:16618929, 12468722, PMID:12481055, PMID:37623603
Traits
sterol biosynthesis, Seedling Lethal, Pale Yellow, Die at Seedling Stage, Slow Growth, Defective Hypocotyl, Abnormal Flowers, Reduced Sterols, Embryo Lethal, plant height, life span, plant growth, seedling lethality