MDH — Sorghum bicolor

Summary

SbMDH (SORBI_3007G137600) on sorghum chromosome 7 encodes a malate dehydrogenase (EC 1.1.1.37) with NAD-L-malate dehydrogenase activity, belonging to the malate dehydrogenase type 1 family. The gene is associated with C4 photosynthesis, the TCA cycle, glyoxylate cycle, malate and carboxylic acid metabolism, and chloroplast organization. It is linked to chloroplast stroma protein import, response to heat, cold, and light stimulus, defence against bacteria, and regulation of transcription. The product localizes to plastid stroma, chloroplast envelope, inner membrane, nucleoid, stromule, and mitochondrial lumen. Associations include photosynthetic rate, respiration rate, chlorophyll content, chloroplast development, high temperature stress, oxidative stress, salt, thermomemory, plastid genome stability, heat tolerance, oxidative stress tolerance, heat stress response, chaperone activity, redox response, and thermotolerance. Related genes in other species link the family to chloroplast development under heat stress and redox response.