CYP — Sorghum bicolor

Summary

SORBI_3007G164300, designated SbSQN and also known as CYP, encodes a cyclophilin-type PPIase (peptidyl-prolyl cis-trans isomerase) with cis-trans proline isomerase activity (EC 5.2.1.8) and cyclosporin A binding capacity. The gene is associated with protein folding, regulation of protein refolding, activation of secondary metabolite biosynthesis, and secondary metabolism. It is linked to responses to abscisic acid, salt, and mannitol, and to activation of the salinity response. The product localises to the chloroplast stroma, cytosol, cytoplasm, nucleus, and plasmalemma. Studies of related cyclophilin family members in rice link the gene family to grass weed traits, though this is not established for sorghum.