COMT — Sorghum bicolor

Summary

SORBI_3007G058400 (COMT/EOMT) on sorghum chromosome 7 encodes a protein with domains including COMT_dimerisation, COMT_C, COMT-like, WH_DNA-bd_sf, SAM-dependent_MTases_sf, and WH-like_DNA-bd_sf. It is annotated with multiple O-methyltransferase activities, including caffeate O-methyltransferase, isoeugenol O-methyltransferase, and flavonoid 3'-O-methyltransferase, as well as ubiquitin ligase substrate adaptor and protein phosphorylated amino acid binding. The gene is associated with serotonin and indole glucosinolate metabolism, regulation of anthocyanin metabolism, flavonol biosynthesis, melatonin anabolism, coumarin anabolism, and secondary metabolite biosynthesis. It has been linked to lignin content, sugar content, reproductive period, IAA content, leaf vein morphology, cell growth, viral disease response, and nematode resistance. Associations include responses to water, mannitol, freezing, and thermal stimuli, as well as pigmentation, phloem transport, seed oilbody biogenesis, and mucilage anabolism during seed coat development. The protein localizes to the cytosol, nucleus, plastid, plasmalemma, plasmodesmata, plant-type cell wall, and stress granules.