AM25 — Sorghum bicolor

Summary

SbAM25 (SORBI_3007G039600) on sorghum chromosome 7 encodes an aquaporin family protein with MIP and aquaporin-like domains. The gene product exhibits transmembrane transporter activities for lactate, arsenite, glycerol, borate, urea, and water, and is associated with the transport of these substrates, including hydrogen peroxide membrane transport. SbAM25 is associated with responses to boron, arsenic, glucose, hypoxia, and defense regulation, as well as phenylpropanoid anabolism and nodulation. The protein localizes to the plasma membrane, lateral plasma membrane, peribacteroid membrane, endoplasmic reticulum, and nucleus. Phenotypic associations connect SbAM25 to boron uptake and deficiency tolerance, arsenite and arsenate tolerance, aluminum resistance and translocation, urea uptake, pollen development, and xylem and root localization. Studies of related genes in other species link the broader gene family to arsenic accumulation, silicon transport, salt stress, reproductive development, and grain traits.