ADH — Sorghum bicolor

Summary

SORBI_3004G343200 (SbADH) on sorghum chromosome 4 encodes an S-(hydroxymethyl)glutathione dehydrogenase, an enzyme with S-(hydroxymethyl)glutathione dehydrogenase (NAD(P)+) and S-nitrosoglutathione reductase (NADH) activities (EC 1.1.1.284). The gene is associated with responses to hypoxia, flooding, and hydrogen peroxide, as well as heat acclimation, seed development, programmed cell death, and cellular respiration. It has been linked to traits including drought tolerance, low temperature stress response, herbicide sensitivity, photosynthetic rate, leaf senescence, plant height, stem thickness, and disease tolerance. Localisation evidence places the product in the cytosol, plastid, mitochondria, nucleus, and plasmalemma. Studies of related genes in other species link the family to hypoxia tolerance, cold stress resistance, and formaldehyde detoxification.