CAD — Sorghum bicolor

Summary

SORBI_3002G195700, designated SbCAD, encodes a probable cinnamyl alcohol dehydrogenase on sorghum chromosome 2. The enzyme exhibits cinnamyl-alcohol, coniferyl-alcohol, 8-hydroxygeraniol and mannitol dehydrogenase activities, binds zinc, and belongs to the CAD-like protein family. SbCAD is associated with lignin content, phenylpropanoid metabolism, secondary metabolite biosynthesis, alkaloid metabolism, C4 photosynthesis, response to water, defense response and signal transduction, and is localised to the cytoplasm. Studies of related genes in other species link the CAD family to additional alcohol dehydrogenase activities (EC 1.1.1.324 and 1.1.1.255).