MS1 — Solanum tuberosum

Summary

StMS1 (PGSC0003DMG400028127) on potato chromosome 10 encodes a cobalamin-independent methionine synthase (EC 2.1.1.14) and also exhibits ADP-glucose pyrophosphatase, ADP-ribose pyrophosphatase, nucleoside diphosphatase, and NAD+ diphosphatase activities, along with DNA-binding transcription factor activity. The gene is associated with methionine biosynthesis, the S-adenosyl-L-methionine cycle, sulfur metabolism, starch metabolism and its regulation, lignin breakdown, and DNA methylation-dependent heterochromatin assembly. It localizes to the chloroplast envelope, stroma, cytosol, mitochondria, plasmodesma, and apoplast. StMS1 is linked to traits including starch and protein content, anthocyanin content, whole plant size, root morphology, disease tolerance, oxidative stress response, and insect damage response. It is also associated with male sterility, pollen exine development, and chromatin silencing. Related genes in other species are linked to seed germination, salt tolerance, and pathogen defense.