EDM1 — Solanum tuberosum

Summary

PGSC0003DMG400028904, designated StEDM1 on potato chromosome 6, encodes a member of the Sgt1-like protein family, characterized by SGS, CS, TPR and HSP20-like chaperone domains. The product exhibits multiple binding activities including Hsp90, ubiquitin ligase, chaperone, kinase and protease binding, along with SUMO transferase and protein serine/threonine phosphatase activities. StEDM1 is associated with upregulation of cellular defense response, respiratory burst involved in defense response, and responses to cold, auxin, humidity, chlorate, and unfolded protein. It localizes to the nuclear matrix, perinuclear region of cytoplasm, SCF complex, stress granule, and vacuole. The gene is linked to traits including disease tolerance, photosynthetic rate, stomatal opening, flowering time, cadmium concentration, brassinosteroid sensitivity, and responses to temperature, light, and oxidative stress. Studies of related genes in other species connect the family to basal defense, disease resistance, heat tolerance, and circadian rhythm.